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Home Page >Online Product Catalog > Primary Antibodies > Natural Resistance Assciated Macrophage Proteins (NRAMP1-2), MTP1, DMT1, Dcytb > Anti-Rat Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, with/without IRE) IgG #4, aff. Pure (Antibodies)

Anti-Rat Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, with/without IRE) IgG #4, aff. Pure

Catalog# Product Description Product Type Antibody Type Size Price
NRAMP24-A Anti-Rat Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, with/without IRE) IgG #4, aff. Pure Antibodies Rabbit-Poly 100 ug $345.00



SpeciesReactivity
Rat

SugApplications
Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the

SugSecAntibodies
http://4adi.com/commerce/ccc2480-secondary-antibodies-rabbit.htm

SugNegativeControl
Non-immune Rabbit IgG Cat# 20009-1

Form
Affinity purified IgG

SugPositiveControl
Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid

Antigen
A 19-aa peptide of rat NRAMP2 (protein accession #, refs 1) ; Designated (NRAMP24 -P or control peptide) conjugated to KLH; Epitope ~Epitope location~ Cytoplasmic domain #4

SpCrossreactivity
The rat NRAMP24-P control peptide sequence is 100% conserved in mouse, 94% in human, 73% in zebra fish NRAMP2. This sequence is common in NRAMP2 with or without IRE isoforms. This antibody will not distinguish between these isoforms. Antibody cross-reactivity in various species has not been established

For research use only, not for diagnostic or therapeutic use.

Data Sheets
NRAMP24-S-A-P.pdf

MSDS

General Information

Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associated Macrophag

Citations
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ADI Product Used Authors, Year, Journal, Title Technique used Comments
DMT1+IRE/NRAMP2 Ab Johnson DM  2005  FEBS Lett. 579, 1923-1929  Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem iron WB  IF  Caco-2 cells
DMT1+non-IRE/NRAMP2 Ab Chong WS  2005  Hum. Reprod. 20, 3532-3538  Expression of divalent metal transporter 1 (DMT1) isoforms in first trimester human placenta and embryonic tissues WB    antibody blocking with control peptide
FP1 ab Wang J  2007  European Journal of Neuroscience, Volume 25, Issue 9: 2766-2772  Ferroportin1 and hephaestin are involved in the nigral iron accumulation of 6-OHDA-lesioned rats Jun Wang, Hong Jiang and Jun-Xia Xie   IHC  rabbit anti-rat FP1 and rabbit anti-rat HP; rat brain
Fpn1 mouse antiserum Qian MZ  2007  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1772, Issue 5, May 2007, Pages 527-532  Expression of ferroportin1, hephaestin and ceruloplasmin in rat heart WB    The rabbit anti-mouse Fpn1 and Heph antiserum; Rat heart
NRAMP-2 ab# NRAMP21 Moos T  2004  J. Neurochemistry 88, 1, 233-245  The significance of the mutated divalent metal transporter (DMT1) on iron transport into the Belgrade rat brain WB  IHC  rat and human brain
NRAMP-2 ab# NRAMP22-A Kovar J  2006  Blood Cells, Molecules, and Diseases, 37, 95-99  Stimulation of non-transferrin iron uptake by iron deprivation in K562 cells WB    The human cell line K562 (erythroleukemia cells
NRAMP-2 ab# NRAMP22-A Moos T  2006  Journal of Neurochemistry, Volume 98, Issue 6: 1946-1958.  Brain capillary endothelial cells mediate iron transport into the brain by segregating iron from transferrin without the involvement of divalent metal transporter 1 WB  IHC  rat and human brain
NRAMP-2 ab# NRAMP22-A Moos T  2004  J. Neurochemistry 88, 1, 233-245  The significance of the mutated divalent metal transporter (DMT1) on iron transport into the Belgrade rat brain WB  IHC  rat and human brain



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