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Home Page >Online Product Catalog > Primary Antibodies > Glutamate Transporters > Anti-Rat EAAC1/EAAT3 IgG #1, aff pure (Primary Antibodies)

Anti-Rat EAAC1/EAAT3 IgG #1, aff pure

Catalog# Product Description Product Type Antibody Type Size Price
EAAC11-A Anti-Rat EAAC1/EAAT3 IgG #1, aff pure Primary Antibodies Rabbit-Poly 100 ug $355.00



SpeciesReactivity
Rat

SugApplications
Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the

SugSecAntibodies
http://4adi.com/commerce/ccc2480-secondary-antibodies-rabbit.htm

SugNegativeControl
Non-immune Rabbit IgG Cat# 20009-1

Form
Affinity purified IgG

SugPositiveControl
Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the “General Information” tan under Product overview section. Control or blocking peptid

Antigen
14aa peptide of rat EAAC1 Designated (EAAC11-P or control peptide). Epitope location ~ C-terminus, cytoplasmic

SpCrossreactivity
The rat EAAC11-P peptide is unique to EAAC1 without significant homology to other glutamate transporters. It is 100% homologous in Mouse, Rat, rabbit, and Human. Antibody crossreactivity in various species is not established.

For research use only, not for diagnostic or therapeutic use.

Data Sheets
EAAC11-S-A-P.pdf

MSDS

General Information

Glutamate is the main excitatory neurotransmitter in the brain. To date five glutamate Transporters have been cloned: GLAST (EAAT1), GLT1 (EAAT2), EAAC1 (EAAT3), EAAT4, and EAAT5. These transporters are believed to be critical in reducing potentially t

Citations
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    showing 1 - 25 of 117   next 25
ADI Product Used Authors, Year, Journal, Title Technique used Comments
EAAC1/EAAT3 ab#EAAC11-A Najimi M  2002  FEBS Lett., 523, s 1-3, 224-228  Cytoskeleton-related trafficking of the EAAC1 glutamate transporter after activation of the Gq/11-coupled neurotensin receptor NTS1 &n   rat C6 glioma cells
EAAC1/EAAT3 ab#EAAC11-A Canolle B  2004  J. Neurochem., 88: 1521 - 1532.  Glial soluble factors regulate the activity and expression of the neuronal glutamate transporter EAAC1: implication of cholesterol &n  
EAAC1/EAAT3 ab#EAAC11-A Ueda Y  2000  Epilepsy Res. 39, 201-209  Sequential change in glutamate transporter protein levels during Fe-induced epileptogenesis &n  
EAAC1/EAAT3 ab#EAAC11-A Ueda Y  2002  Mol. brian. Res. 104, 120-126  Expression of glutamate transporters and ionotropic glutamate receptors in GLAST knockout mice &n   glast knockout mice
EAAC1/EAAT3 ab#EAAC11-A Gonazalez MI  2003  J. Neurosci., 23: 5589 - 5593.  Phorbol Myristate Acetate-Dependent Interaction of Protein Kinase C and the Neuronal Glutamate Transporter EAAC1 &n   IP rat C6 glioma cells
EAAC1/EAAT3 ab#EAAC11-A Harrington EP  2007  Epilepsia, Volume 48, Issue 1 doi: 10.1111  Altered Glutamate Receptor—Transporter Expression and Spontaneous Seizures in Rats Exposed to Methylazoxymethanol in Utero &n   rat tissues
EAAC1/EAAT3 ab#EAAC11-A Deitch JS  2002  J Neurol. Sc. 193, 117-126  GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1 &n   Formalin-fixed, paraffin-embedded tissue
EAAC1/EAAT3 ab#EAAC11-A Rome S  2002  J. Nutr. 132, 1009-1011  The Regionalization of PepT1, NBAT and EAAC1 Transporters in the Small Intestine of Rats Are Unchanged from Birth to Adulthood &n   rat intestine, paraffin sections
EAAC1/EAAT3 ab#EAAC11-A Alexander GM  2000  J. Neurochem. 74, 1666-1673  Elevated Cortical Extracellular Fluid Glutamate in Transgenic Mice Expressing Human Mutant (G93A) Cu/Zn Superoxide Dismutase &n   no difference; data not shown
EAAC1/EAAT3 ab#EAAC11-A Ueda Y  2001  J. Neurochem. 76: 892-900  Collapse of extracellular glutamate regulation during epileptogenesis: down-regulation and functional failure of glutamate transporter function in rats with chronic seizures induced by kainic acid &n  
EAAC1/EAAT3 ab#EAAC11-A Tohgo A  2005  Molecular and Cellular Neuroscience 31, 326-333  Impaired cerebellar functions in mutant mice lacking DNER &n   mouse brain, 4%PF
EAAC1/EAAT3 ab#EAAC11-A Bruening S  2006  Journal of Neurochemistry, Volume 99, Issue 3: 892-899.  The anxiety-like phenotype of 5-HT1A receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA–glutamate system &n   mouse brain synaptosomes
EAAC1/EAAT3 ab#EAAC11-A Najimi M  2005  BBA 1668, 195-202  Pertussis toxin-sensitive modulation of glutamate transport by endothelin-1 type A receptors in glioma cells &n   rat C6 glioma cells
EAAC1/EAAT3 ab#EAAC11-A Boehm U  2005  Cell 123, 683-695  Feedback Loops Link Odor and Pheromone Signaling with Reproduction &n   mouse brain
EAAC1/EAAT3 ab#EAAC11-A Ueda Y  2000  Exp. Brain Res. 133, 334-340  Molecular Regulation of glutamate and GABA transporters proteins by valproic acid in rat hippocampus during epileptogenesis &n  
EAAC1/EAAT3 ab#EAAC11-A Lim J  2005  Invest. Ophthalmol. Vis. Sci. 46, 2867-2877  Molecular Characterization of the Cystine/Glutamate Exchanger and the Excitatory Amino Acid Transporters in the Rat Lens &n   rat lens, antibody blocking with control peptide blocking, paraformaldehyde fixed tissues
EAAC1/EAAT3 ab#EAAC11-A Schicho R  2005  Brain Res. 1039, 108-115  Nociceptive transmitter release in the dorsal spinal cord by capsaicin-sensitive fibers after noxious gastric stimulation &n   rat brain
EAAC1/EAAT3 ab#EAAC11-A Aoyama K  2006  Nature Neuroscience 9, 119-126  Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse &n   mouse
EAAC1/EAAT3 ab#EAAC11-A Ma K  2006  J Biol Chem. 2006 Jul 28;281(30):21250-5. Epub 2006 May 24.  The transcription factor regulatory factor X1 increases the expression of neuronal glutamate transporter type 3 &n   rat glioma C6 cells
EAAC1/EAAT3 ab#EAAC11-A Guillet BA  2005  Neurochemistry Int. 46, 337-346  Differential regulation by protein kinases of activity and cell surface expression of glutamate transporters in neuron-enriched cultures &n   rat brain
EAAC1/EAAT3 ab#EAAC11-A Gonzalez MI  2005  Journal of Neurochemistry 94, 1180-1188  Evidence that protein kinase Ca interacts with and regulates the glial glutamate transporter GLT-1 &n   IP mouse synaptosome
EAAC1/EAAT3 ab#EAAC11-A Chen J-C  2005  NeuroPharmacol. 49, 703-714  Down-regulation of the glial glutamate transporter GLT-1 in rat hippocampus and striatum and its modulation by a group III metabotropic glutamate receptor antagonist following transient global forebrain ischemia &n   rat brain
EAAC1/EAAT3 ab#EAAC11-A Gonzalez MI  2003  J. Neurosci., Jul 2003; 23: 5589.  Phorbol Myristate Acetate-Dependent Interaction of Protein Kinase C and the Neuronal Glutamate Transporter EAAC1 &n   IP C6 glioma cells, a cell line that endogenously expresses EAAC1
EAAC1/EAAT3 ab#EAAC11-A Vermeiren C  2004  Neurochemistry Intl. 46, 137-147  Molecular and functional characterisation of glutamate transporters in rat cortical astrocytes exposed to a defined combination of growth factors during in vitro differentiation &n   rat brain
EAAC1/EAAT3 ab#EAAC11-A Wang S  2006  Pain, 120, 78-85  Downregulation of spinal glutamate transporter EAAC1 followingnerve injury is regulated by central glucocorticoid receptors in rats &n   rat brain



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