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Home Page >Online Product Catalog > Primary Antibodies > Beta-Site APP-Cleaving Enzymes (BACE/Asp2/Asp1) > Human beta-site APP cleaving enzyme (BACE/Asp2) Control/blocking peptide #2 (Peptide)

Human beta-site APP cleaving enzyme (BACE/Asp2) Control/blocking peptide #2

Catalog# Product Description Product Type Antibody Type Size Price
BACE12-P Human beta-site APP cleaving enzyme (BACE/Asp2) Control/blocking peptide #2 Peptide 100 ug $95.00



SugApplications
Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization.

SpeciesReactivity
Human

Form
Antigen/blocking Peptide

Antigen
10-aa peptide of mouse BACE/Asp2 ; Designated (BACE12-P or control peptide) conjugated to KLH; epitope location ~ N-terminus, Extracellular domain

SpCrossreactivity
The mouse BACE12-P sequence is 100% conserved in human and 90% in rat BACE/Asp2. No significant sequence homology exists with BACE2/Aps1, a homolog of BACE, or other Asps. Antibody crossreactivity in various species is not established.

For research use only, not for diagnostic or therapeutic use.

Data Sheets
BACE12-S-A-P-C.pdf

MSDS

General Information

¿-amyloid (A¿) deposition in the brain is the hallmark of Alzheimer's Disease (AD). To initiate A¿ formation, ¿-secretase cleaves APP at the N-terminus of A¿ to release APPs¿ (~100 kDa soluble NT-fragment), and C99, a 12-kDa CT membrane fragment. Altern

Citations
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