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Home Page >Online Product Catalog > Primary Antibodies > Hyperpolarization-activated Cyclic Nucleotide-gated channel 1-4 (HCN1-4) > Anti-Mouse Hyperpolarization-activated Cyclic Nucleotide-gated channel 3 (HCN3) IgG, aff pure (Primary Antibodies)

Anti-Mouse Hyperpolarization-activated Cyclic Nucleotide-gated channel 3 (HCN3) IgG, aff pure

Catalog# Product Description Product Type Antibody Type Size Price
HCN31-A Anti-Mouse Hyperpolarization-activated Cyclic Nucleotide-gated channel 3 (HCN3) IgG, aff pure Primary Antibodies Rabbit-Poly 100 ug $355.00



SpeciesReactivity
Mouse/Rat

SugApplications
Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the

SugSecAntibodies
http://4adi.com/commerce/ccc2480-secondary-antibodies-rabbit.htm

SugNegativeControl
Non-immune Rabbit IgG Cat# 20009-1

Form
Affinity purified IgG

SugPositiveControl
Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the “General Information” tan under Product overview section. Control or blocking peptid

Antigen
17-aa peptide from mouse HCN3- (1); (Gene Accession #NP032253) Designation (#HCN31-P, control/blocking peptide) conjugated to KLH; epitope location ~ cytoplasmic, C-terminus, after the CNBD domain

SpCrossreactivity
The HCN31-P peptide is 100% conserved in mouse, 94% in rat, and 82% in human HCN3. No significant sequence homology of HCN31-P is seen with other HCNs or any other protein. Antibody reactivity in various species is not known

For research use only, not for diagnostic or therapeutic use.

Data Sheets
HCN31-S-A-P.pdf

MSDS

General Information

HCN3 or HAC3 (rat 780-aa, mouse 779-aa, human 703 aa) has been detected in brain but its expression was much less than other HCNs. Its expression was also detected in liver, lung, and kidney of mouse by some researchers but not by others.

Citations
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    showing 1 - 2 of 2  
ADI Product Used Authors, Year, Journal, Title Technique used Comments
HCN-3 ab # HCN31-a Wells JE  2007  International Endodontic Journal., 40, 715–721, 2007  Hyperpolarization-activated channels in trigeminal ganglia innervating healthy and pulp-exposed teeth &n   ab used @1:1000-1:250; Rat trigeminal ganglia
HCN-3 Ab #HCN31-A Strauss U  2004  Eur. J. Neuros.19, 11, 3048-3058  An impaired neocortical I h is associated with enhanced excitability and absence epilepsy &n   rat brain



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