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Home Page >Online Product Catalog > Primary Antibodies > Hyperpolarization-activated Cyclic Nucleotide-gated channel 1-4 (HCN1-4) > Anti-Human Hyperpolarization-activated Cyclic Nucleotide-gated channel 1 (HCN1) IgG, aff pure (Primary Antibodies)

Anti-Human Hyperpolarization-activated Cyclic Nucleotide-gated channel 1 (HCN1) IgG, aff pure

Catalog# Product Description Product Type Antibody Type Size Price
HCN11-A Anti-Human Hyperpolarization-activated Cyclic Nucleotide-gated channel 1 (HCN1) IgG, aff pure Primary Antibodies Rabbit-Poly 100 ug $355.00



SpeciesReactivity
Human/Mouse

SugApplications
Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the

SugSecAntibodies
http://4adi.com/commerce/ccc2480-secondary-antibodies-rabbit.htm

SugNegativeControl
Non-immune Rabbit IgG Cat# 20009-1

Form
Affinity purified IgG

SugPositiveControl
Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the “General Information” tan under Product overview section. Control or blocking peptid

Antigen
14-aa peptide from (Gene Accession # NP 034538) human/mouse HCN1 (1); Designation (#HCN11-P, control/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain

SpCrossreactivity
The HCN11-P peptide is 100% conserved in human, mouse and 92% in rabbit and rat HCN1. No significant sequence homology of HCN11-P is seen with other HCNs or any other protein. Antibody reactivity in various species is not known

For research use only, not for diagnostic or therapeutic use.

Data Sheets
HCN11-S-A-P.pdf

MSDS

General Information

HCN1, also known as Brain cyclic nucleotide channel gated 1, BCNG1 or HAC-2 (mouse/rat 910 aa, human 749-aa), is primarily expressed in brain. In mouse, HCN1 is mainly expressed in the neocortex, the CA1 region of the hippocampus, the superior colliculus

Citations
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    showing 1 - 2 of 2  
ADI Product Used Authors, Year, Journal, Title Technique used Comments
HCN-3 ab # HCN31-a Wells JE  2007  International Endodontic Journal., 40, 715–721, 2007  Hyperpolarization-activated channels in trigeminal ganglia innervating healthy and pulp-exposed teeth &n   ab used @1:1000-1:250; Rat trigeminal ganglia
HCN-3 Ab #HCN31-A Strauss U  2004  Eur. J. Neuros.19, 11, 3048-3058  An impaired neocortical I h is associated with enhanced excitability and absence epilepsy &n   rat brain



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