Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization.
18-aa peptide of rat GPR14 (1) ; Designated (GPR14-P or control peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain
The 18 AA rat GPR14-P control peptide sequence is 100% conserved in mouse and 66% in human GPR14. No appreciable homology is seen with other GPCR. Antibody crossreactivity in various species is not established
For research use only, not for diagnostic or
Recently, an orphan human G-protein coupled receptor homologous to rat GPR14 has been identified as the receptor for UII (2). GPR14 is expressed predominantly in cardiovascular tissue. Human UII effectively stimulated total peripheral resistance in anes
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