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Home Page >Online Product Catalog > Primary Antibodies > Apoptosis/AIF/Survivin/Aven/FLASH/PUMA/Apaf-1 > Anti-Mouse Apoptosis Inducing Factor (AIF) IgG #1, aff pure (Primary Antibodies)

Anti-Mouse Apoptosis Inducing Factor (AIF) IgG #1, aff pure

Catalog# Product Description Product Type Antibody Type Size Price
AIF11-A Anti-Mouse Apoptosis Inducing Factor (AIF) IgG #1, aff pure Primary Antibodies Rabbit-Poly 100 ug $355.00



SpeciesReactivity
Mouse

SugApplications
Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the

SugSecAntibodies
http://4adi.com/commerce/ccc2480-secondary-antibodies-rabbit.htm

SugNegativeControl
Non-immune Rabbit IgG Cat# 20009-1

Form
Affinity purified IgG

SugPositiveControl
Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the “General Information” tan under Product overview section. Control or blocking peptid

Antigen
20-aa peptide from mouse AIF (1); Designation (AIF11-P, control peptide) Epitope location ~ N Terminus

SpCrossreactivity
Mouse AIF11-P control peptide is 95% conserved in rat, and 61% in human AIF. No significant sequence homology is detected with other ferredoxins. Antibody cross-reactivity in various species has not been studied.

For research use only, not for diagnostic or therapeutic use.

Data Sheets
AIF11-S-A-P.pdf

MSDS

General Information

Mouse and human AIF are 92% homologous. The C-terminus of AIF shares significant homology with several bacterial ferredoxins, and the N-terminus has two mitochondrial localization signal. The N-terminal 1-101 AA are cleaved to produce mature AIF.

Citations
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    showing 1 - 25 of 47   next 22
ADI Product Used Authors, Year, Journal, Title Technique used Comments
AIF Ab#AIF11-A Dirks AJ  2003  Free Radical Biol. Med. 36, 27-39  AGING AND LIFELONG CALORIE RESTRICTION RESULT IN ADAPTATIONS OF SKELETAL MUSCLE APOPTOSIS REPRESSOR, APOPTOSIS-INDUCING FACTOR, X-LINKED INHIBITOR OF APOPTOSIS, CASPASE-3, AND CASPASE-12 &n   rat. Xiap etc from others
Livin Ab #LIVIN11-A ka H  2003  Am. J. Pathol., 163: 413 - 422  Temporal and Spatial Patterns of Expression of Inhibitors of Apoptosis in Human Placentas &n   human placenta, -ve results for WB, nuclear staining
Livin Ab #LIVIN11-A Tu SP  2003  Cancer Res., 63: 7724 - 7732.  Suppression of Survivin Expression Inhibits in Vivo Tumorigenicity and Angiogenesis in Gastric Cancer &n   gastric epithelial cancer cells
NOD1 Ab #NOD11-A Sterka D  2006  Journal of Neuroimmunology, 179, 65-75  Characterization of nucleotide-binding oligomerization domain (NOD) protein expression in primary murine microglia &n   mouse neuronal and microglial
Parkin Ab #PARK11-A Hase A  2002  Brain Res. 930, 143-149  Characterization of parkin in bovine peripheral nerve &n   human brain,
Parkin/park-3 Ab #PARK11-A Choi P  2000  Neuroreport. 11(12):2635-2638,  Parkin is metabolized by the ubiquitin/proteosome system &n   human tumors; park-1, -2 from cc etc
Survivin ab #SURV11-A Beierle EA  2005  J. Surgical Res., 127, 21-28  VEGF-Mediated Survivin Expression in Neuroblastoma Cells &n   Human neuroblastoma cells (IMR-32, CCL-127
Survivin ab #SURV11-A Mohapatra S  2005  Cancer Res. 65: 7717 - 7723  Accumulation of p53 and Reductions in XIAP Abundance Promote the Apoptosis of Prostate Cancer Cells &n   human prostate cancer cell lines LNCaP, PC3, and DU145
Survivin ab #SURV11-A Mega S  2006  Diseases of the Esophagus, Volume 19, Issue 5: 355-359.  Immunohistochemical analysis of nuclear survivin expression in esophageal squamous cell carcinoma &n   esophagela cancer cells
Survivin ab #SURV11-A Ikeguchi M  2002  Clin Cancer Res. 8, 3131-3136  Inducible Nitric Oxide Synthase and Survivin Messenger RNA Expression in Hepatocellular Carcinoma &n   human tumors/also I-NOS from chemic/ADI
Survivin ab #SURV11-A Mohapatra S  2003  Cancer Res., 63: 8523 - 8530  Roscovitine Inhibits STAT5 Activity and Induces Apoptosis in the Human Leukemia Virus Type 1-Transformed Cell Line MT-2 &n   iap1/2 from transduction
Survivin ab #SURV11-A Tran Jennifer  1999  Biochem. Biphys. Res. Commun. 264, 781-788  Marked induction of the IAP family anti-apoptotic proteins survivin and XIAP and VEGF in vascular endothelial cells &n  
Survivin ab #SURV11-A nakanishi K  2002  Virchows Archiv 441(6):559-63  survival in patients with transitional cell carcinoma of the upper urinary tract &n   paraffin sections/autoclave/urinary bladder tumors
Survivin ab #SURV11-A Nefedova Y  2004  Blood, 103: 3503 - 3510  Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines &n   human cell lines
Survivin ab #SURV11-A Nakamura S  2005  Eur J Haematol 2005: 75: 212–220  Etodolac inhibits EBER expression and induces Bcl-2-regulated apoptosis in Burkitt's lymphoma cells Etodolac inhibits EBER expression and induces Bcl-2-regulated apoptosis in Burkitt's lymphoma cells &n   lymphoma cells
Survivin ab #SURV11-A Okada E  2001  Cancer Lett. 163, 109-116  Survivin expression in tumore cell nuclei is a function of favorable prognosis in gastric cancer patients &n   formalin-fixed, paraffin embedded
Survivin ab #SURV11-A Tu SP  2003  Cancer Res., 63: 7724 - 7732.  Suppression of Survivin Expression Inhibits in Vivo Tumorigenicity and Angiogenesis in Gastric Cancer &n   gastric epithelial cancer cells
Survivin ab #SURV11-A Tu SP  2005  Gastroenterology, Volume 128, Issue 2, February 2005, Pages 361-375  Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant &n   gastric epithelial cancer cells
Survivin ab #SURV11-A Yamamoto K  2004  Leukemia Res. 28, 1203-1211  Expression of IAP family proteins in myelodysplastic syndromes transforming to overt leukemia &n   pf/paraffin HT29 human colon adenocarcinoma cells
Survivin ab #SURV11-A McManus DC  2004  Oncogene 23, 8105 - 8117  Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics &n   human MDA-231 cells
Survivin ab #SURV11-A Li Y F Sarkar  2005  Mol. Cancer Ther., 4: 389 - 398  Gene expression profiling revealed novel molecular targets of docetaxel and estramustine combination treatment in prostate cancer cells &n   LnCap cells
Survivin ab #SURV11-A Shankar SL  2001  J. Neurochemistry 79, 2, 426  Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways &n   msn cells/
Survivin ab #SURV11-A Beierle EA  2005  J. Surgical Res. 127, 21-28  VEGF-mediated survivin expression in neuroblastoma cells &n   Human neuroblastoma cells (IMR-32, CCL-127
Survivin ab #SURV11-A Chantalat L  2000  Molecular Cell, 6, 183-189  Crystal Structure of Human Survivin Reveals a Bow Tie¯Shaped Dimer with Two Unusual -Helical Extensions &n  
Survivin ab #SURV11-A Nakamura S  2006  Leukemia Res., 30, 123-135  Etodolac induces apoptosis and inhibits cell adhesion to bone marrow stromal cells in human myeloma cells &n   Human myeloma-derived cell lines, RPMI 8226 and MC/CAR



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